5 Essential Elements For mif

5 Essential Elements For mif

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MIF is needed to the interaction amongst NLRP3 and also the intermediate filament protein vimentin, which happens to be important for NLRP3 activation. additional, we reveal that MIF interacts with NLRP3, indicating a role for MIF in inflammasome activation impartial of its role as a cytokine. These details progress our comprehension of how MIF regulates inflammation and recognize it as an element significant for NLRP3 inflammasome activation.

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